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Its important for patients to follow their healthcare providers dosing recommendations and discuss any persistent side effects, as there are often adjustments or supportive treatments that can help manage these symptoms

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[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Kasina S.V.S.K., Baradhi K.M

Challenges in the optimization of multi-receptor agonists Although multi-receptor agonists such as tirzepatide exhibit enhanced effectiveness, their development poses distinct obstacles that need careful attention

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The protective effect of GLP-1 RAs was particularly evident in patients with obesity (aHR: 0.61, 95% CI: 0.500.77), whereas no significant benefit was noted in non-obese individuals (aHR: 0.94, 95% CI: 0.671.31)
