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"Constipation from GLP-1s can be compounded by the fact that people are eating less," says Hamilton, "resulting often in less fiber consumption and less stool bulk overall." Many people also drink less fluid to avoid feeling overly full on GLP-1 medications, which can also lead to constipation

The cultural impact is huge: these drugs are reshaping dating, intimacy, and the very idea of desirability
doi: 10.1016/0031-9384(83)90120-8 32 JohnsonWGCorriganSALemmonCRBergeronKBCruscoAH

A BMI value in the chart is NOT sufficient to assign an obesity code physician documentation of the obesity diagnosis is required per FY2026 ICD-10-CM Official Guidelines, Section I.C.21.c.3
Some researchers continue indefinitely, while others cycle off after reaching their weight loss goals