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Because Tirzepatide activates an additional hormonal pathway, many obesity specialists believe it may provide stronger appetite suppression and metabolic benefits compared to Semaglutide alone

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Semaglutide: Through once-weekly dosing, this long-acting GLP-1 lowers blood glucose and supports sustained weight loss

Azithromycin, another macrolide antibiotic with motilin receptor activity, is emerging as an efficacious alternative to erythromycin with equivalent profiles for accelerating gastric emptying in patients with gastroparesis, with the added benefit of a longer duration, a better side effect profile, and a lack of P450 interaction and the associated risks [142]

Tirzepatide and diuresis were continued, while antihypertensives and statin therapy were held