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doi: 10.3389/fendo.2022.1004044 73 SyedYY

GLP-1RAs mitigate these adverse impacts by enhancing fatty acid oxidation via the Creb5/NR4a1 signaling axis, thereby reducing mitochondrial damage, lipid accumulation, and ATP deficiency (77, 78, 83)

Liu et al., 2020a)

Others take two to three months

Tuttle KR, Lakshmanan MC, Rayner B, et al

Exendin 4-based agents Exendin-4, a 39-amino acid peptide with 53% sequence homology to human GLP-1 [ Figure 2 ], was originally isolated from Heloderma suspectum lizard venom by using an amino acid sequencing assay targeting peptides with an amino-terminal histidine residue (His 1 ) (83)