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Description
In the SURPASS-2 trial, patients with obesity and T2D who received tirzeapatide (5 mg weekly) achieved greater HbA1c and body weight reductions than those receiving semaglutide (1 mg weekly) during the 40 week study (64) despite comparable putative GLP-1R occupancy at these doses (65)
Berkheimer adds
The FBI has the data
Curr Drug Targets
This may include folks who are elderly who could have serious side effects from drastic weight loss and reduced muscle mass and those with known nutrient deficiencies
New study confirms GLP-1 medications are safe for mental health in diabetes
