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This review explores the complex interplay between hyperkalemia and the use of guideline-directed medical therapies (GDMT), such as reninangiotensinaldosterone system inhibitors (RAASi) and steroidal mineralocorticoid receptor antagonists (sMRAs), including spironolactone and eplerenone, which are currently recommended in guidelines for improving outcomes in heart failure with reduced ejection fraction (HFrEF)

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The IQVIA discussion mentioned this study in noting that, The GLP-1 category of drugs is affecting both sides of the pharmacy counter. The GLP-1 Rx therapy category index high on medicines that tend to be more consumer-driven and -demanded (in terms of personal spending) compared with other drug categories

The diabetes drug, Ozempic, works by affecting reward centers in the brain, which doctors believe may make people less prone to addiction.

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GLP-1 prescription costs vary significantly based on medication type, provider network, and compounding pharmacy selection