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In addition, weight loss is a consistent finding in clinical trials investigating GLP-1RAs (27)

[DOI] [PubMed] [Google Scholar] 16.Risk of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss

Why This Conversation Matters: The Truth About GLP-1 Medications GLP-1 medications work by regulating appetite, insulin signaling, and blood sugar
SGLT-2 inhibitors Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are a class of drug that promotes glucose excretion in the urine by inhibiting its reabsorption in the proximal tubule

Thats why its common for patients to require a second course of medication two to three years after the initial treatment, after they have regained a significant amount of weight
