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Notably, the insulinotropic and glucagonostatic effects are glucose dependent, and therefore the risk of hypoglycemia is very low during treatment with a GLP-1 RA

She called that "reassuring," while noting it is as much as the data can show for now

But interestingly, the studies show that cravings seem to come back after two years, especially for sweets

It may also help through weight loss, since losing weight can improve insulin resistance

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Stress reduction may also play a role, as chronic psychological stress and elevated cortisol levels can impair metabolic hormone regulation