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Furthermore, SEM normalized the expression of autophagy-related proteins in the substantia nigra and striatum in mice, including P62, ATG7, Beclin, and LC3, leading to the alleviation of oxidative stress and promotion of neurovascular reconstruction [31,32,39]
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This estimated timeline assumes: Consistent adherence to your calorie target Stable activity levels Normal metabolic response to calorie restriction Use this timeline to set realistic expectations and avoid disappointment if progress seems slower than hoped

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