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Mechanical valve replacement, for example, is typically the most durable option for a young patient, but the need for systemic anticoagulation during pregnancy often makes it an unattractive option for some patients

In the NMA, semaglutide 2.4 mg was associated with a greater percent weight CFB with 52 weeks of treatment versus all available comparators in all populations, except phentermine 15 mg/topiramate 92 mg in the T2DM population

Patients with high-response genetic markers may achieve meaningful weight loss at 0.5 mg or 1.0 mg, allowing them to skip or shorten higher doses and reduce side effect burden

While most prescription drugs have little to no brand recognition, these and other GLP-1s have become household names seemingly overnight, and their brand names have become synonymous with weight loss

Cardiovascular protective properties of incretin-based therapies in type 2 diabetes

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