why are glp 1 drugs so expensive GLP-1 Medications Expensive? Costs Explained GLP-1 Costs Explained: Managing Coverage
Description
GLP-1 receptors are not only expressed in the pancreas, but also in peripheral tissues, including the central nervous system, heart, kidney, lung, and gastrointestinal tract [8,9]
For example, in the lungs, GLP-1s may reduce the inflammatory response, improve oxidative stress, regulate protease/anti-protease imbalance, improve airway mucus homeostasis, and reduce airway remodeling to provide benefit in patients with COPD
Glycemic control appears to be more effective when both receptors are activated [99, 100]
Gregory, G
Diabetes 58: 2148-2161, 2009
Sci Rep 9 , 8447 (2019)
