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Currently, there are three FDA-approved oral GLP-1s on the market in the US: Rybelsus, which is approved for type 2 diabetes, the Wegovy pill, which is approved for weight loss, and Foundayo, which is also approved for weight loss

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The GLP1R rs6923761 variant, assessed in genetic panels, influences GLP-1 receptor sensitivity and may contribute to variable nausea responses

This research was supported by the Department of Defense (W81XWH-18-1-0206), The Hartwell Foundation, the Schwartz Research Fund and the National Institute of Diabetes and Digestive and Kidney Diseasesfunded Integrated Islet Distribution Program Award Initiative (to BPC)