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Description
Cell Tissue Res
There is an additive effect of using a DPP-4 inhibitor alongside other agents that decrease blood glucose

PIONEER 1: randomized clinical trial comparing the efficacy and safety of oral semaglutide monotherapy with placebo in patients with type 2 diabetes

The most common side effects of these drugs are mild gastrointestinal (GI) issues
Researchers found that people who took semaglutide lost, on average, 3.6% of their body weight after three months

The protective cardiovascular effects of GLP-1RAs can be through improving glycemic control, as reducing HbA1c can improve blood pressure, body weight, hyperlipoproteinemia, and inflammation
