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In many cases, the more likely explanation is the weight loss process: a prolonged caloric deficit, nutritional gaps, hormonal shifts, or stress

Am J Physiol Renal Physiol (2010) 298(1):F17786

Similarly, in another meta-analysis including 47 RCT and more than 23 thousand patients, patients receiving different GLP1RAs had a mean difference in weight of -5 kg relative to placebo [10]

The truth is more nuanced than a simple yes or no

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GLP-1 receptors are abundantly expressed throughout the gastrointestinal tract, and semaglutide's activation of these receptors produces several physiological changes that can affect bowel function
