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As large-scale trials like EVOKE and EVOKE + unfold, integrating insights from estrogen biology could enhance the impact of GLP-1based therapies in neurodegenerative disease

GLP-1 resistance has recently been reported in T2D patients 20

Liraglutide was the first GLP-1 receptor analogue approved for the management of obesity, thus starting the new era of gastrointestinal peptide agonist pharmacotherapy for the treatment of both diabetes and obesity

GLP-1 agonists stimulate the pancreas to release insulin and suppress the release of another hormone called glucagon, both of which help control blood sugar levels in people with type 2 diabetes

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