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For these reasons, limited treatment options exist for this patient population

However, newer GLP-1 medications, such as semaglutide and tirzepatide, have demonstrated superior efficacy in clinical trials

The body therefore tends to preserve fat stores while trimming unneeded muscle mass unless regular exercise signals that muscle remains necessary and adequate protein intake supports its maintenance

Tamoxifen can cause side effects, and weight gain might be one of them for some people

Tirzepatide maintenance and SURMOUNT-4 trial follow-up
