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For these reasons, limited treatment options exist for this patient population

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However, newer GLP-1 medications, such as semaglutide and tirzepatide, have demonstrated superior efficacy in clinical trials

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The body therefore tends to preserve fat stores while trimming unneeded muscle mass unless regular exercise signals that muscle remains necessary and adequate protein intake supports its maintenance

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Tamoxifen can cause side effects, and weight gain might be one of them for some people

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Tirzepatide maintenance and SURMOUNT-4 trial follow-up

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