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Description
There is no silver bullet to weight loss or is there
Thats why the FDA gives it a boxed warning
Objective This systematic review aims to synthesise published evidence on respiratory adverse events temporally associated with GLP-1 RA therapy in adults, characterise their patterns and severity, appraise the risk of bias using validated design-appropriate tools, describe proposed pathophysiological mechanisms, and grade the certainty of evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework
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Women benefit most when we treat menopause as the metabolic inflection point it isnot just prescribing GLP-1s in isolation, but considering hormone therapy, addressing sleep disruption (which drives cortisol and undermines any weight loss effort), and building strength to counter the lean mass loss these medications can cause
