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As of April 9, 2026, retatrutide is not FDA-approved, and Lilly says it is available only through Lilly clinical trials

In the SURMOUNT-3 trial, tirzepatide demonstrated clinically meaningful additional body weight reductions (6.9%) in adults who were overweight or obese following initial weight loss with intensive lifestyle intervention [73]

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HDL can be raised by increasing physical activity and focusing on a whole-foods, low refined carbohydrate and low trans-fat diet

Candidates are determined during consultation based on health history, goals, BMI, and provider discretion
