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Review response to treatment after 36 months, keeping in mind that pioglitazone has a slower onset of action than other agents

was funded by an MRC New Investigator Research Grant (MR/M012646/1) and a Diabetes UK Early Career Small Grant (16/0005441)

Avoid caffeine as for some people with RLS, caffeine is a trigger

Larger production volumes lead to cost reductions in raw materials, labor, and overhead

Our team can explain eligibility, documentation needs, next steps, and whether this program may be appropriate based on your medical evaluation

Clinical Judgment Two decades of use, tens of millions of patients worldwide, and a safety record that (when you look at the full body of evidence rather than the social media horror stories) is actually quite solid for a drug this widely prescribed