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Strategy 2: Start at a higher dose if appropriate
The mechanisms differ in clinically meaningful ways

[49] [50] Gallbladder and biliary risk [edit] Semaglutide treatment is associated with an increased risk of biliary disease, specifically gallstones (cholelithiasis)

Endocr Rev 25 : 426457 Diano S et al

These symptoms may indicate anaphylaxis, a medical emergency requiring prompt treatment with epinephrine