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Prescription GLP-1 receptor agonist medications have received significant attention following clinical trial outcomes

Nat Commun (2015) 6:7715.10.1038/ncomms8715 172 DuferMHorthKWagnerRSchittenhelmBProwaldSWagnerTFet alBile acids acutely stimulate insulin secretion of mouse beta-cells via farnesoid X receptor activation and K(ATP) channel inhibition

Systemic delivery of peptides by the oral route: formulation and medicinal chemistry approaches

Liraglutide restored proper autophagic flux by alleviating the accumulation of P62 (an autophagy dysfunction marker) in the lacrimal gland, reduced oxidative damage by enhancing clearance of ROS and promoting cellular repair mechanisms, and potentially addressed dry eye syndrome (Sun et al., 2025)

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