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Certain patient factors may increase susceptibility to constipation on GLP-1 therapy
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12:1048-1057 [PubMed: 20977575] 257
In the placebo condition, participants with obesity showed an imbalance common in overeating: their brain's reward areas lit up when the cue signaled the impending milkshake, indicating heightened craving or wanting, but their neural response during the actual tasting was blunted, indicating reduced liking
Observational reports have noted changes in alcohol consumption among some patients prescribed tirzepatide for diabetes or obesity
