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Description
The core was prepared using the solvent casting technique, similar to initial burst-release MNs
(3) If the patient has high-risk factors for gastrointestinal bleeding, such as a history of gastrointestinal diseases (e.g., peptic ulcer disease and its complications), age 65 or older, or concurrent use of corticosteroids, anticoagulants, or non-steroidal anti-inflammatory drugs (NSAIDs), preventive measures should be implemented

Shima Hadidchi, MD, Explains the Difference
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According to the population pharmacokinetic analysis, exposure changes approximately 1.1 percent per kilogram across the 70 to 120 kilogram range

Combining them in someone with prior pancreatitis history is a meaningful risk multiplier
