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Description
Understanding what to expect and how to respond enables most users to continue treatment through temporary discomfort that resolves with time
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In the randomized STEP 2 trial (intent to treat: 1,210 adults with overweight or obesity and T2D), the estimated treatment difference from baseline to week 68 for semaglutide 2.4 mg versus placebo was 6.2 percentage points (95% CI 7.3, 5.2
longum and L
Elrod RD, Weinberg DA
What stands out here is not just the magnitude of effect (e.g., ~4 kg more weight loss), but also the higher adherence, persistence, and cost-effectiveness per responder in everyday care settings
