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The high discontinuation rate among patients without type 2 diabetes was striking, reinforcing concerns that insurance barriers limit sustained use for those seeking GLP-1 receptor agonists for weight management, Emanuel said

People should discuss all medicines they are taking, including over-the-counter and herbal products, to help avoid interactions

doi: 10.1038/nrn2867 31 CollinsS

Dosing frequency varies from twice daily to once weekly, depending on the agent

Wegovy is FDA-approved specifically for chronic weight management in adults with obesity or overweight with a related health condition

Conclusions: GLP-1 receptor agonists, alone or in combination with GIP and/or glucagon receptor agonists, represent promising, effective pharmacotherapies for the treatment of MASLD/MASH