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In patients with type 2 diabetes, semaglutide is reported to improve glycaemic control dose-dependently, decreasing HbA 1c levels by 1.7% (18.7 mmol/mol) vs 0.5% (5.5 mmol/mol) with placebo and 4.8 kg of weight loss vs 1.2 kg with placebo, relative to baseline

Injectables In a seminal March 2021 New England Journal of Medicine study, adults receiving a weekly 2.4 mg injection of semaglutide for about 15 months lost 15% of their body weight 35 pounds, on average

doi: 10.3233/JAD-143090 170 Perez-CruzCNolteMWvan GaalenMMRustayNRTermontATangheAet al

26 This means the proportion of lean mass relative to total body mass often increases , indicating an overall improvement in body composition

At least three had been expired for nearly nine months