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[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Li M., Ding L., Cao L., Zhang Z., Li X., Li Z., Xia Q., Yin K., Song S., Wang Z., et al

An estimated $200-$230 billion in annual branded revenue will lose exclusivity protection between 2025 and 2030, with drugs like Keytruda ($29B+ in 2024 sales), Eliquis ($13B+ for BMS alone), and Opdivo concentrated in a narrow 2026-2028 window

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After years of struggling with obesity, Tony Tierno finally lost 50 pounds on the blockbuster weight loss drug Zepbound
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