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This rapid increase in prescription rates followed the recent approval of two GLP-1R agonists, semaglutide (Ozempic, Wegovy) and liraglutide (Victoza), for weight management in obese or overweight patients

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Goal: metabolic health improvement without maximum weight loss Some researchers are primarily interested in retatrutide for metabolic health markers: insulin sensitivity, liver fat reduction, lipid profiles, and inflammatory markers

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By increasing the levels of GLP-1 in the body, semaglutide helps to reduce feelings of hunger and promote feelings of fullness, leading to a decrease in overall food intake and weight loss