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Ann Intern Med 2019

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Two major neuronal populations present in the arcuate nucleus control caloric intake and energy expenditure: one population co-expresses orexigenic agouti-related peptide (AgRP) and neuropeptide Y and the other expresses the anorexigenic anorectic neuropeptides proopiomelanocortin and cocaine- and amphetamine-regulated transcript (POMC/CART)

105 , e2710e2716 (2020)
What they want to understand is whether there are other peptide-based options, what those options do, and how they compare to what is now the dominant name in injectable weight loss
