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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Anderson HD, et al

Green or Amber

We just called it "normal." My Own Volume Knob When I was deep in my food dysfunction using engineered food substances to manage every difficult emotion I wasn't just numbing the grief, the fear, the loneliness

A proof-of-concept, open-label trial of weekly exenatide (2 mg, 48 weeks, 50 patients) showed an advantage in the unified multiple system atrophy rating scale (UMSARS, parts I and II combined score) at 48 weeks compared with best medically treated participants, but no difference in more objective secondary measures or biomarkers (neurofilament light chain [NfL], CSF -synuclein oligomers) (165)

Singh AK

Subsequently, in the large randomised placebo-controlled FIDELIO-DKD trial including adults with type 2 diabetes and CKD, finerenone reduced the risk of the primary kidney outcome (a composite of kidney failure, sustained eGFR decline 40% or kidney death) by ~20% [69]