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Investigations conducted at 2023 have shown that vitamin D may also increase GLP-1 levels through the improvement of a healthy gut microbiome

Eur J Pharmacol (2012) 674(2-3):2806

Structure-Function of the Glucagon Receptor Family of G Protein-Coupled Receptors: The Glucagon, GIP, GLP-1, and GLP-2 Receptors

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Its simultaneous activation of three receptor pathways GLP-1R for appetite suppression and insulin secretion, GIPR for augmented insulin response and central appetite modulation, and GCGR for energy expenditure and hepatic fat mobilisation produces metabolic effects that exceed what single or dual agonism can achieve [4][8][9]

Bloomgarden Z., Liraglutide and Calcitonin, Journal of Diabetes 2 (2010): 223224