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The Danish pharmaceutical firm also said the studys design was limited as it was not conducted as a randomized controlled trial, in which patients are randomly assigned to one or two groups before being compared to a control group

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It is important to note that regulatory bodies including the MHRA and EMA continue to monitor the safety profile of GLP-1 receptor agonists, including any potential psychiatric effects

Gastrointestinal symptom profile: The most commonly reported adverse effects directly relate to delayed gastric motility

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Reductions in plasma amino acids and glucagon were suggested to indicate successful GcgR and GLP-1R targeting [96]