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If baseline ALT or AST levels exceed three times the upper limit of normal (ULN), evaluation for underlying causes is appropriate, though this need not necessarily delay semaglutide initiation if benefits are deemed to outweigh risks

Both hyperglycemia and hypoglycemia during hospitalization are associated with increased complications, prolonged lengths of stay, higher readmission rates, and elevated mortality
Pregnancy risk predictor tools (mWHO, CARPREG II, ZAHARA) are a crucial component of pre-conception counseling to help predict which women with existing cardiovascular disease are at highest risk for adverse maternal outcomes