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2016Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

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37 Oxidative stress induced by inflammation and toxicity driven by cytokines may further the decay of the nigrostriatal pathway, thereby hastening the progression of idiopathic PD

[DOI] [PubMed] [Google Scholar] 19.Yau K, et al

This matches what I see in my practice

The sudden drop in signals at the moment of sensory detection or food cognition may reflect the abrupt recognition of an anticipated resolution of energy deficit, rather than being driven by ingestive or hormonal signals which typically act over minutes to hours [50]