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Ex-4 treatment upregulates the expression of the proteins critical for mitochondrial biogenesis, including peroxisome proliferator-activated receptor- coactivator-1 (PGC-1), nuclear respiratory factor-1 (NRF-1), and transcription factor a, mitochondrial (Tfam)

2023bSemaglutide in HFpEF across obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial

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These findings suggested that PF augmented the expression levels of EMT biomarkers, which were markedly suppressed by dulaglutide treatment

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The speakers also mention several companies that work in the integrated functional medicine space and can assist with practitioner training and fulfillment