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The GLP-1 receptor agonist drug class has revolutionized obesity treatment, but key unmet needs persist

In the ACHIEVE-1 phase 3 trial, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes

The company has acquired a European competitor, Zava, which already has 1.3 million customers for a range of productsincluding some obesity treatmentsin the UK, Ireland, Germany and France

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