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The companies said there is no risk to patients, while an investigation into the active pharmaceutical ingredient-related concern is underway.

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Why this matters It reinforces that endpoint language matters (missing non-inferiority no efficacy) It keeps the spotlight on amylin + GLP-1 biology as a serious strategy It shows how obesity therapeutics is becoming a multi-platform race, not a single-drug race Novos message appears clear: the company still sees a meaningful role for CagriSema, and is continuing development with future studies (including REDEFINE 11 / higher-dose exploration)