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When weight loss happens more gradually, the body tends to preserve more lean mass

JAMA 2025, 333, 113114

Assessment of gastric emptying using a low fat meal: establishment of international control values

While these health benefits are well established, information is sparse on the drugs effects across the bodys organ systems

Rekha Kumar, an endocrinologist and obesity specialist at Weill Cornell Medicine and New York Presbyterian

Similarly the weight loss seen with Exenatide and some other early GLP-1 drugs was thought too limited to win approval for the treatment of obesity (Gilbert, Rosenthal, March 2024)
