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Our results suggest that GLP-based therapies can be a safe approach for weight loss in patients with history of nephrolithiasis, although longer term studies following a larger population of obese stone formers will be needed to definitively confirm the effect of GLP-based therapy on stone incidence and recurrence

A confirmatory analysis also showed that 33% of patients in the semaglutide group achieved both endpoints (resolution of steatohepatitis and improvement in fibrosis) compared with 16% of those receiving placebo

But optimal ranges can vary by the individual and by the routes that you're taking

The loading phase, ~ 20 g per day for 5 to 7 days, is optional

Most patients see weight or inches lost within the first week of treatment

Efficacy and Safety of Oral Semaglutide versus Placebo in Subjects with Type 2 Diabetes Mellitus treated with insulin
