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Description
3) missing residues in N-terminus (R24-A28), stalk (S129-R134), and ICL2 (S258-S261) were modelled using MODELLER 40

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Outcomes differ: Approximately 70% of patients experienced significant weight loss after 6 months of semaglutide treatment

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(15.9 kg), or 15% of their weight, and results can be sustained for 2 years

Maintaining consistent hydration may help minimise these symptoms
