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Z., Rooney M

However, the emergence of newer treatments and increased competition have impacted its sales performance

Given the natural fluctuations in hormone levels and the intricate rhythms of human physiology throughout the day and over a persons lifetime, there is concern about the uncertain health ramifications of sustained elevation of incretin activity over decades of treatment

doi: 10.1185/03007995.2012.654850

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Astrup A., Rssner S., Van Gaal L., Rissanen A., Niskanen L., Al Hakim M., Madsen J., Rasmussen M.F., Lean M.E.J

Eligible patients entered run-in phase where any OAD other than metformin were stopped and patients were prescribed glargine