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The following best practices reflect standard pharmaceutical research guidance for lyophilised peptide compounds, as set out in the MHRA GCP Guide, EU GMP Annex 13 (Investigational Medicinal Products), and EU/UK GDP guidelines
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The proportion of male patients per treatment group ranged from 47% to 57% in PIONEER 1 to 5 and 8, but was greater in PIONEER 6, representing 68% to 69% of enrolled patients, as well as in PIONEER 9 and 10, where 68% to 83% of patients were male
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