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SESN2-regulated autophagy is mechanistically involved in liraglutide-mediated alleviation of IR As part of our current study, we examined whether SESN2-mediated autophagy may contribute to improve IR by liraglutide

Maintain 6 mg for at least 8-12 weeks to assess response before considering further escalation

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Hyperglycemia plays a critical role in DKD initiation

One study, in which exenatide or placebo was continuously infused intravenously into healthy, fasted individuals, demonstrated that subjects infused with exenatide while clamped at euglycaemic concentrations of glucose (5.0 mmol/l), secreted much greater amounts of insulin than the placebo-infused counterparts (350 pmol/min vs

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