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Lilly's Oral GLP-1, Orforglipron, Demonstrated Meaningful Weight Loss and Cardiometabolic Improvements in Complete ATTAIN-1 Results Published in The New England Journal of Medicine

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Tummino, PhD, Nimbus president of research and development, stated at the time

[7] The primary mechanism underlying HMB's effectiveness centers on its dual action: stimulating muscle protein synthesis while simultaneously suppressing muscle protein breakdown