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In the comparison of GLP-1 use vs non-use, 1,610 BC patients with obesity were included

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All eligible individuals who initiated the program within the study period were included, resulting in a sample reflective of real-world clinical practice

Emerging evidence suggests that microbial metabolites not only regulate endogenous GLP-1 secretion but may also influence therapeutic response to GLP-1 receptor agonists, raising the prospect of microbiome-guided treatment strategies in obesity and type 2 diabetes

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