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At Wondr Health, weve seen how each phase brings new challenges, and how ongoing support can make the difference between short-term progress and long-term transformation

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Sleep, stress, and life Poor sleep increases hunger hormones (ghrelin) and reduces fullness hormones (GLP-1, CCK, PYY)

Importantly, these responses could also be explained by the redundancy of insulinotropic signals from the gut or nervous system during oral versus IP glucose loads, but in the end still demonstrate that -cell GLP-1r, in and of themselves, are not necessary for oral glucose tolerance

2) insulin resistance leading to decreased glucose uptake by peripheral tissues (muscle and adipose)

Activities most people take for grantedlike climbing a flight of stairswere physically draining, leaving her feeling restricted and discouraged