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The actions of the hormone (and the medication) can help to improve blood sugar (stimulates insulin secretion), stop glucagon action (blocks stored sugar from going into the bloodstream), reduce blood sugar spikes (slows digestion/stomach emptying), and lead to eating less (promotes satiety)

Metformin is a first-line drug for treating type 2 diabetes 14

Additionally, semaglutide is contraindicated in patients with a history of suicidal attempts or current suicidal ideation, as it may exacerbate these conditions

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