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While Im excited that patients may soon have more options, enthusiasm should not blind us to the risks
doi: 10.4158/EP.15.6.540
2013, 2014, Ferdinand et al
It found that saxagliptin significantly increased the risk of HF by 21%, especially in patients at high risk for cardiovascular, while no signal was detected for other DPP4i

Adverse events The analysis of adverse events between the GLP-1RAs and placebo groups revealed that the most frequently reported adverse effects were nausea, vomiting, and diarrhea
