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Cocaine use disorder is a chronic condition marked by strong cravings, loss of control over drug use, and a tendency to relapse after periods of abstinence

This adaptive thermogenesis can slow weight loss over time and, if caloric intake isn't adjusted accordingly, may contribute to weight stabilization or modest regain

Whilst these drugs can offer meaningful benefits for people living with obesity, their effects on kidney function deserve careful consideration, particularly for those with pre-existing renal conditions

For example, older adults and those who take diuretics, which are water pills that lower blood pressure, may be more sensitive

A calorie deficit occurs when you consume fewer calories than your body uses daily

[DOI] [PubMed] [Google Scholar] 883.Ding K.H., Zhong Q., Isales C.M