faa semaglutide Pilots and Ozempic: Medical Certification Guidelines – PlexusDx Weight Loss - Aviation Medical

"The FDA regulates brand-name GLP-1 drugs such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) and approves those drugs in very specific doses," says Katy Williams, MD, an MU Health Care family medicine doctor and bariatric medicine specialist

Data presented at the 61st Annual Meeting of the European Association for the Study of Diabetes (EASD) 2025, a few months back, have provided new insights into the potential role of metformin within a GLP-1 RA-based regimen continuum, with findings that extend beyond glycaemic outcomes into territory that carries greater clinical weight

SURMOUNT-3 For the SURMOUNT-3 trial, patients who lost at least 5% of their body weight after a 12-week intensive lifestyle intervention lead-in period that included a low-calorie diet, exercise and weekly counseling sessions, were randomly assigned to receive either tirzepatide or placebo for 72 weeks to assess the efficacy and safety of the drug

Ozempic , approved for Type 2 diabetes, has also been repurposed for obesity under the brand Wegovy

Mild nausea or dry mouth can occur, but theyre generally very well tolerated

Spironolactone is generally considered a safe diuretic that doesnt cause potassium loss